BDNF and Stroke: In addition to EGF, several growth factors and hormones regulate the proliferation and birth of new neurons in vivo and in vitro isolated from neurogenic niches in mammals, which are controlled by behavioral changes, sociosexual stimuli, stress, stroke injury, lactation, pregnancy, among others (see the review for steroid hormones [46, 47], prolactin [48, 49], brain-derived neurotrophic factor [50], progesterone [51] and oxytocin [52]).