Moreover, high PFKFB3 expression was not related to DFI [1.82 (0.64–5.21), p = 0.264, Table 2; p = 0.257, Fig. 1G] but to DSS [AHR = 2.43 (1.36–4.37), p = 0.003, Table 2; p < 0.001, Fig. 1H] in patients with oral cancer. The gene discussed is PFKFB3; the disease is lip and oral cavity carcinoma.