PTK2 and non-small cell lung carcinoma: BALB/c nude mice were injected intravenously (i.v.)with FTO-overexpressing and control A549 cells to establish the in vivo model of NSCLC metastasis and were then given DMSO or the FAK inhibitor defactinib (VS6063) (25 mg/kg, daily), gavage administration, beginning in the fifth week after injection.