Group B Strep sepsis was significantly associated with multiple cell clusters, including C8_DC, C9_STOM, C10_ULK1, C12_mix, C13_UBE2Z, and C16_B, and its signature genes, including CKAP4, CPEB4, TSPO, and TXN, were significantly upregulated in multiple relevant clusters (Additional file 2: Figure S4F). This evidence concerns the gene CKAP4 and Sepsis.