We found that, in addition to sex (OR = 0.305; [0.120/0.771]; p = 0.012), hypertension (OR = 0.213; [0.043/1.069]; p = 0.060) and dyslipidaemia (OR = 0.142; [0.160/1.236]; p = 0.077), the serum sclerostin level was an independent estimator of CDV risk (OR = 1.026; [0.999/1.054]; p = 0.064) in T2D patients. This evidence concerns the gene SOST and Hypertension.