Interestingly, Huang et al. discovered that SOX9 overexpression was not only significantly associated with tumor (T, P = 0.03), node (N, P = 0.000), and metastasis (M, P = 0.032) categories in clinical samples of NSCLC, but also significantly promoted the migration, invasion and epithelial-mesenchymal transition (EMT) of NSCLC cells [16]. The gene discussed is SOX9; the disease is neoplasm.