CCL2 and allergic asthma: Ang-(1–7) has been reported to improve allergic asthma by suppressing eosinophils, Th2 cytokine secretion and macrophage infiltration, and downregulating the phosphorylation of CCL2, mitogen-activated protein kinase (MAPK) and nuclear factor kappa-B (NF-κB) pathways [14–17].