Based on the ROC curves, the following thresholds were selected to define increased laboratory indicators for identifying acute HCA ≥ stage 2: CRP ≥ 6.90 mg/L (sensitivity, 0.700; specificity, 0.529), NLR ≥ 11.93 (sensitivity, 0.506; specificity, 0.674), and MLR ≥ 0.57 (sensitivity, 0.675; specificity, 0.572). This evidence concerns the gene CRP and hepatocellular adenoma.