To focus particularly on CML, we co-cultured two different CML cell lines (K562 and LAMA84) with and without primary NK cells that were either unexpanded or expanded with IL-2 and feeder cells and profiled these 6 different conditions with scRNAseq as previously described [33]. The gene discussed is IL2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.