After quality control, a total of 7550 tumor cells were classified into diffuse and intestinal types according to the expression of previously provided marker genes for the intestinal type (EPCAM, MUC13, and COL3A1)34 and diffuse type (cancer stem cell marker CD44)35 (Fig. 1h-k) and 11 clusters according to their transcription characteristics (Fig. 1i). This evidence concerns the gene CD44 and neoplasm.