SERPINA2 and nonpapillary renal cell carcinoma: 53 ARGs were found in the ccRCC samples of the TCGA database with significant expression differences in normal and ccRCC samples using |log FC|> 2, p < 0.05 as the screening criterion (Fig. 1A), including 12 down-regulated ARGs and 41 up-regulated ARGs (Fig. 1B).