Among the top 10 pathways, four were related to cancer (Glioblastoma, molecular mechanisms of cancer, Chronic Myeloid Leukemia, Pancreatic Adenocarcinoma), two to hepatic signaling (Hepatic Fibrosis, Hepatic Stellate Cell Activation), and four related to growth and cell cycle regulation (Senescence, PTEN, NGF, Cardiac Hypertrophy Signaling). The gene discussed is PTEN; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.