TNF and cancer: Due to the properties of their customized nanomaterials and advanced smart nanoparticles for cancer therapy, these biomimetic CMCNPs have recently attracted a lot of interest.68 For instance, platelet membrane-coated nanoparticles with Dox loaded into the inner nanoparticles and tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) put onto the outer membrane have been successfully created.