Mothers working in bidi rolling establishment reported a significant 310 g reduction in birth weight (mean and SD=2.350±0.420 kg vs 2.660±0.350 kg; p<0.001) of their babies.89 Another case–control study reported that occupational tobacco exposure in pregnant bidi workers led to a significant reduction in cord serum leptin (adjusted (adjusted for maternal gestational hypertension, prematurity and birth weight) mean difference (95% CI)=−4.5 ng/mL (−8.82, –0.19); p=0.041). The gene discussed is LEP; the disease is preeclampsia.