Patients with a higher AST/ALT ratio were lower in weight, more likely to drink alcohol, had higher severity of illness scores on admission, lower systolic blood pressure, and a higher prevalence of various medical conditions, including myocardial infarction, liver disease, sepsis, acute kidney injury, cardiac arrest, congestive heart failure, peripheral vascular disease, and cardiogenic shock. The gene discussed is GPT; the disease is congestive heart failure.