An increased AST/ALT ratio has been linked to worse outcomes in patients with a range of health conditions, including heart failure [15, 16], acute myocardial infarction [17, 18], cardiac arrest [19], sepsis [20], hypertension [21], type 2 diabetes [10], and COVID-19 [22, 23], among others. This evidence concerns the gene GPT and myocardial infarction.