Among the 22 identified CAL protein-coding gene products, CBX2, DACT1, G3BP1, MED1, PLK4 and YAP1 were self-drive LLPS proteins and their LLPS clients RNF2, CSNK2A1, FUS, POU5F1, SASS6 and TEAD1 were identified from the PhaSepDB2.0 database to form six LLPS protein-coding gene pairs for subsequent GSVA & survival analysis in cancers in which CAL protein-coding gene-set GSVA was of prognostic value for both OS and PFS. This evidence concerns the gene PLK4 and cancer.