ICAM-1 concentration was higher in OSA patients (200.23 ± 45.99 mg/dL) compared to controls (292.27 ± 78.12 mg/dL, p<0.001), furthermore, severe-OSA group indicated a higher concentration of ICAM-1 compared to mild-OSA (260.8 ± 66.30 mg/dL) (p = 0.048), and there was no considerable difference between moderate-OSA (304.9 ± 81.7 mg/dL) with mild-OSA and severe-OSA (312.9 ± 78.83 mg/dL) (Fig 1B). Here, ICAM1 is linked to obstructive sleep apnea syndrome.