CCR5 and parasitic infectious disease: From this, we identified 26 common DEGs downregulated in Tr1 cells from both parasitic diseases, including Ccr7, Tcf7, and Bcl6, as well as 29 upregulated DEGs, including Il10, Havcr2, Prdm1, Ccr2, Ccr5, Maf, and Lag3 (Figure 1E).