Proportions of total IFNγ+ cells were also significantly higher in CD56hi CD16+ and CD56− CD16+ NK cells from pSS patients, while IFNγ+ cells within CD56dim CD16+ and CD56hi CD16− NK cell populations were only significantly increased in untreated pSS patients (Appendix Fig S1B and C, and Table S2). Here, IFNG is linked to peeling skin syndrome.