These data are particularly relevant since high MICa/b expression has been observed in SGs from pSS (Schrambach et al, 2007) and polymorphisms on MICa/b have been linked to higher susceptibility to develop Sjögren's syndrome and with higher levels of soluble MICa/b in the plasma of these patients (Carapito et al, 2017). The gene discussed is MICA; the disease is Sjogren syndrome.