It is worthy of note that in our previous study, Py infection inhibits the CCR10-mediated PI3K/Akt/GSK-3β/Snail signaling pathway in a murine liver cancer model, but in our current study, Pc infection inhibits the CXCR2/TGF-β-mediated PI3K/Akt/GSK-3β/Snail signaling pathway in murine lung cancer models. This evidence concerns the gene AKT1 and liver cancer.