The 16 identified genes were primarily enriched in metabolic pathways (ko01100), valine, leucine, and isoleucine degradation (ko00280), cardiac muscle contraction (ko04260), motor proteins (ko04814), and hypertrophic cardiomyopathy (ko05410) (Supplementary Table S14). The gene discussed is IMMT; the disease is hypertrophic cardiomyopathy.