The results revealed a significant enrichment in pathways related to both lipid metabolism (such as butanoate metabolism, fatty acid metabolism, PPAR signaling pathway, insulin secretion, and fatty acid degradation) and muscle development (including cardiac muscle contraction, adrenergic signaling in cardiomyocytes, hypertrophic cardiomyopathy, dilated cardiomyopathy, and regulation of actin cytoskeleton) (Figure 4B; Supplementary Table S13). Here, INS is linked to hypertrophic cardiomyopathy.