SOD1 and congestive heart failure: ↑ Enlarged abdomen and ascites; ↑ mortality rate; ↓ body weight, heart weight and ratio of heart to body weight; ↑ cardiomyopathic changes and congestive heart failure; ↓ heart cell DNA, RNA and protein synthesis; cell vacuolization, myofibril loss and disarrangement; ↓ GSH-Px, SOD; ↑ MDA