DLL1 and systemic lupus erythematosus: Although studies have suggested a role for Notch signaling in LN progression[43] and attempted to intervene at key steps in the pathway to block disease, they did not obtain the desired results.[44] So far, only one study applied DLL1 intervention in LN with an endpoint to block splenic MZB cells in lupus‐prone (NZB×NZW) F1 mice,[44] which unfortunately failed.