Furthermore, the IF of Ki-67 in animal transplanted cancer samples revealed that the group of mice administered with M2/sh-1592#2-Exos or M2-Exos + Annexin V exhibited reduced expression of this protein compared to the group of mice administered with M2/sh-NC-Exos or M2-Exos alone (Fig. S3D). Here, ANXA5 is linked to cancer.