AKT1 and neoplasm: Genes related to cervical cancer progression was found by enrichment analysis before treatment, including CTNNB1, CCR7, AKT1, SLIT2, CDK6, etc. Human SAIL4 (sal-like 4), the new discovered proto oncogenes encode transcription factors that acted at the level of stem cells, SAIL4 protein can recognize and bind to CTNNB1 promoter region and trans‐activating CTNNB1 for accelerated expression β- Catenin, which promoted cell proliferation and the formation of tumor cervical cancer cells [39].