Previous studies by Yvonne Kienast et al. showed that the anti-Ang2-VEGFA cross-reactive mAb, a novel bispecific human IgG1 antibody, inhibits the hematopoietic spread of tumor cells to other organs (Schmittnaegel et al. 2017; Felcht et al. 2012). Here, ANGPT2 is linked to neoplasm.