Pancreatic cancer cells also showed enhanced activity of several PDAC-specific regulons, including PPARG, KLF3, FOXL1, MAFK and GLI2 (Fig. 3a,b and Extended Data Fig. 6b), and several regulons shared with squamous cells, such as TP63, FOSL1 and ELK3 (Fig. 3a and Extended Data Fig. 6c). The gene discussed is PPARG; the disease is pancreatic neoplasm.