These findings are supported by existing literature, which suggests that TP53 is expressed at different levels in non-cancerous naevi compared to MM patients43 In addition, another study demonstrated that the upregulation of TP53 could be suggestive of cytotoxicity in the cell, which indicates that TP53 plays an important role in maintaining the integrity and stability of cells44. Here, TP53 is linked to Miyoshi myopathy.