As shown in Table 1, XIST and miRNA155 along with Gab2, TAK1, VCAM-1, ICAM-1, IL-1ꞵ, and TNF-α were identified as the final independent variables associated with APS with P values 0.004, 0.01, 0.03, 0.005, < 0.0001 < 0.0001, 0.005 and < 0.0001 respectively. The gene discussed is ICAM1; the disease is autoimmune polyendocrinopathy.