Additional studies found that the transcription factor YY1 (yin yang 1) together with LINC01134, miR-324-5p, and IGF2BP1 (Insulin-like growth factor 2 mRNA binding protein 1), could form a positive feedback loop that mediates the progression of hepatocellular carcinoma [22]. This evidence concerns the gene YY1 and hepatocellular carcinoma.