MYC and hepatocellular carcinoma: A previous study by Sanghvi et al (2019) reported that the knockdown of FN3K could promote the downregulation of Nrf2 target proteins in murine MYC/sgKeap1 HCC liver tumor isografts and similarly in three pairs of FN3K-proficient and FN3K-deficient human xenografts (Huh1, H460, and H3255) models [4].