The relationship between Cav1 and prostate specific antigen (PSA) is controversial, some studies suggest that there is a significant correlation between Cav1 and PSA in castration-resistant prostate cancer (CRPC) [61, 63, 64, 71, 72, 76], but some studies suggest that there is no significant correlation between Cav1 and PSA of difference stage and grade of PCa [14, 41, 69, 70, 73, 74] (Table 1). Here, CAV1 is linked to posterior cortical atrophy.