As circulating aAb to FUBP1 and ENO1 was increased in PDA patients, their prognostic role was evaluated by assessing their levels with the risk of death in the two cohorts, namely cohort 1 and cohort 2, in which resected and non-resected patients were recruited at different times, from 2002 to 2012, and 2012 to 2020, respectively (Table 1). The gene discussed is FUBP1; the disease is Patent ductus arteriosus.