KLK3 and prostate neoplasm: In-vivo evaluation of FLT-CAS micelles found that micellar FLT had better anti-tumor efficacy than free drug, as seen by a decrease in PSA serum level, prostate and seminal vesicle relative weights, and histological alterations. Furthermore, FLT-CAS micelles were reported to effectively reduce prostate tumor cell proliferation, limit tumor angiogenesis, and improve tumor apoptotic induction. Hepatotoxicity was also reduced in drug micelles compared in free medications