According to the qPCR results, styrax liquidus administration increased the expression of Bax, Bad, Bak1, p53, Apaf-1, Caspase2, Caspase3a, Caspase9, and Caspase12 and decreased the expression of Bcl-2 and Bcl-XL in HEp-2 cancer cells (P < 0.05). This evidence concerns the gene APAF1 and cancer.