DEK-NUP214 [t(6;9)(p22;q34)] was associated with AML, NUP214-ABL1 was identified in T-ALL patients, the rarest leukemia NUP214 fusion protein is SQSTM1-NUP214: to date, only two cases have been reported, one in ALL and the other in AML. This evidence concerns the gene SQSTM1 and acute myeloid leukemia.