PLK1 and cancer: To mine the response of LUAD patients to anti-cancer drug treatment, wedissected the linkage between the expression of prognostic feature genes andthe IC50 values of drug antagonists, with results displaying asignificant positive linkage between the expression of the PLK1 andIC50 value of 5-Fluoro deoxy uridine 10mer (cor = 0.510), while theexpression level of NT5E showed a significant negative linkage with theIC50 values of Idarubicin (cor = -0.510), XR- 5944 (cor = -0.501),and Fluorouracil (cor = -0.499)(Fig. 7A).