Table S1 shows the distribution of baseline thyroid hormones sensitivity indices stratified by age groups. Of note, there was no significant difference of baseline thyroid hormones sensitivity indices among people with and without incident diabetes during follow-up (Figure S1). However, the thyroid hormones sensitivity indices at follow-up were cross-sectionally correlated with prevalent diabetes (Figure S2). Table S2 shows the baseline characteristics after including 1047 participants with thyroid dysfunctions. The gene discussed is TG; the disease is diabetes mellitus.