CD274 and glioblastoma: FUS-aided immunoPET imaging of glioblastoma. To validate the benefits of applying FUS to target PD-L1 with 89Zr-DFO-C4Fc-MUT, immunoPET imaging was performed in a GBM model with (FUS group) and without (sham group) FUS-induced BBB permeabilization before the injection.