We found that some genes showed a downward trend in terms of their expression by podocytes in the NS-IgAN group, including the canonical marker genes (NPHS1 and CLIC5), the genes encoding membranous nephropathy-associated autoantigens (PLA2R1 and THSD7A), and genes that have not been extensively investigated in podocytes, such as PCOLCE2 and PTGDS (Figure 4C). This evidence concerns the gene NPHS1 and membranous glomerulonephritis.