AVEN was highly expressed in six types of cancer compared to normal tissue: colon adenoma (COAD), Kidney renal clear cell carcinoma (KIRC), Kidney renal papillary cell carcinoma (KIRP), Lung adenocarcinoma (LUAD), Lung squamous cell carcinoma (LUSC), and Thyroid carcinoma (THCA) (Figure 2A). The gene discussed is AVEN; the disease is colon adenocarcinoma.