ACT Genomics Co. Ltd. (Hong Kong) offers a RUO ACTOnco + kit that covers 440 genes with the glioma-related ones (IDH1, IDH2, BRAF, CDKN2A, CDKN2B, CIC, FUBP1, NOTCH1, etc.)for solid tumor molecular profiling compatible with the Ion Torrent platform (Jan et al., 2022). Here, NOTCH1 is linked to central nervous system cancer.