NUP205 and ciliopathy: Collectively supported by genetic evidence (biallelic or homozygous mutations of NUP205), cilia-related phenotypes (LR asymmetry defects and SRNS), the role of ciliogenesis (disrupted cilia number and length upon NUP205 depletion) and subcellular localisation at the cilium base (Braun et al., 2016; Chen et al., 2019; Marquez et al., 2021), previous findings underscore NUP205’s role in cilia bases and human ciliopathy.