POMC and neoplasm: Functioning tumors make up the vast majority (90%) of pituitary adenomas [2, 3, 8, 9], with the prolactin hormone (PRL) tumor prolactinoma, being the most prevalent histological type in children, followed by the adrenocorticotropic hormone (ACTH)-secreting tumor, corticotropinoma, and the growth hormone (GH) secretor somatotropinoma [8, 9].