Consequently, it can be concluded that TA gel treatment after stroke can significantly enhance neuroplasticity in the peri-infarct zone, as PSD95 and Vglut1 containing as well as the WB results of synaptophysin and PSD95 proved the enhancement of synaptic plasticity, and Golgi staining demonstrated the improvement of dendritic plasticity. The gene discussed is SYP; the disease is Stroke.