One study found that THCA cases in TCGA were grouped according to RNA expression of tumor stem cell markers and analyzed for recurrence-free survival between groups, showing that the low CD24 expression group had a significantly worse 12-year recurrence-free survival rate, CD24 participates in the molecular subtype identification of PTC, and high PROM 1, high ALDH 1A 3, and low CD24 in the tall cell variant of papillary thyroid carcinoma have significantly poorer recurrence-free survival rates [26]. The gene discussed is CD24; the disease is differentiated thyroid carcinoma.