SCARNA12 and cancer: To explore the role of SCARNA12 in CRC, we analyzed the expression level of SCARNA12 in CRC and adjacent normal tissue samples from the cancer genome atlas (TCGA) database (P < 0.001, Fig. 1a), gene expression omnibus (GEO) database, GSE87211 (P < 0.001, Fig. 1b), GSE89076 (P = 0.0163, Fig. 1c), UALCAN database (P < 0.001, Fig. 1d) and gene expression profiling interactive analysis (GEPIA) database (Fig. 1e).