Till date, several snoRNAs are dysregulated in CRC and function as oncogenes or cancer-suppressor genes (e.g., SNORD12C [21], SNORA21 [22], SNORA24 [23], SNORA42 [24], SNORD44 [25], SNORD57 [26], and SNORD78 [21]). The gene discussed is SNORA80E; the disease is colorectal carcinoma.