We found no significant correlation between the serum Ang-2 and the Ang-2 level in the tumor epithelial (p = 0.330, Spearman’s rho − 0.079) or endothelial (p = 0.600, Spearman’s rho − 0.041) immunohistochemistry (IHC) staining. Here, ANGPT2 is linked to neoplasm.