To evaluate whether integrins β1 and α6 are indeed involved in B4GALT1-regulated migration and invasion, blocking antibodies against integrin β1 and α6 were incubated with B4GALT1 knockdown or knockout HCC cells and then cells were subjected to transwell migration and Matrigel invasion assays. The gene discussed is B4GALT1; the disease is hepatocellular carcinoma.