Our data showed that B4GALT1 knockdown did not evidently alter 58 phospho-RTK levels and their downstream signaling molecules p-AKT and p-ERK in PLC5 cells (Supplementary Fig. S11), suggesting a minor role of RTKs in the B4GALT1-regulated invasiveness of HCC cells. Here, AKT1 is linked to hepatocellular carcinoma.