Both the mPKCεI and vePKCεI mice exhibited normal gait and extension responses on the hind limb after repeated administration of the PKCε inhibitor, indicating the absence of damage to the lumbosacral plexus (Fig. 6A vs. 6B), and PKCεI also not affected on hyperglycemia (Fig. 6C) or body weight (Fig. 6D). This evidence concerns the gene PRKCE and Hyperglycemia.